ABSTRACT
A multicenter retrospective study was conducted to assess the clinical spectrum of 30 severe acute respiratory syndrome coronavirus (SARS-CoV-2)-positive children with idiopathic nephrotic syndrome. Difficult to treat nephrotic syndrome was found to be a high-risk group with a high incidence of acute kidney injury and mortality.
Subject(s)
COVID-19 , Nephrotic Syndrome , Child , Humans , Nephrotic Syndrome/complications , SARS-CoV-2 , Retrospective StudiesABSTRACT
The outbreak of COVID-19 made the world act differently in business. Preventive steps taken by governments to shut down the road, rail, air and water transportation disrupted supply chains of most of the businesses. Whereas supply chains of essentials like food and pharmaceutical kept working in stressed environment. This paper is highlighting the cost of supply chain due to the outbreak of COVID-19 as a pandemic. The main stakeholders of a supply chain such as supplier, manufacturer, distributor, retailer and customer were tweaked to protect people from infection. New norms such as sanitisation, social distancing, use of personal protective gears increased the lead time and escalated the cost of supply chain management significantly. AHP has been used to model the cost of supply chain management citing a case study of three key industries. It has been seen that the restricted human movement remained pivotal in sky rocketing cost of supply chain. © 2022 Inderscience Enterprises Ltd.
ABSTRACT
This retrospective study describes the clinical profile, risk of infection and outcome of coronavirus disease-19 in immunocompromised children. It was found that children on immunosuppressant medication has 2.89 times increased risk of infection (P=0.01). Disease manifestation was asymptomatic (P=0.01) or mild with predominant gastrointestinal symptoms (P=0.02) without alteration in immunosuppressive treatment regime.
ABSTRACT
The coronavirus outbreak is a rapidly evolving pandemic, placing unprecedented strain on health-care systems. COVID-19 presents challenges for management of children with renal diseases especially those receiving long-term immunosuppressive medications, including renal transplant recipients and those with chronic kidney disease and acute kidney injury requiring dialysis. Our preparedness for managing this vulnerable group of children is the need of the hour. The purpose of this article is to provide guidance to caregivers and health care personnel involved in management of children with renal diseases and to ensure patient well-being, while protecting staff from infection.